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ProgestPure is a highly bioavailable and natural topical progesterone serum providing 20 mg of bioidentical progesterone in each 1 ml serving. It is made from yams - it is then modified in the lab for the progesterone molecule to resemble a human progesterone molecule.


  • Natural bioidentical progesterone can normalize hormone imbalances with fewer side-effects than synthetic progestins.
  • Reproductive age- Supporting progesterone levels in the body may increase the likelihood of a healthy cycle.
  • Menopausal / post-menopausal age- Supporting progesterone levels in the body may help make this significant life change more pleasant.

Made with non-GMO ingredients. This product is free of parabens, mineral oil, and petroleum. 

 Suggested Use*:

  •  Apply 1-2 times per day to smooth skin areas, such as wrists, inner arms or thighs, throat, neck, abdomen or chest, or
  • as directed by a health care practitioner.
  • For optimal use, rotate the areas of application.
  • Menstruating women: Apply 1 ml of ProgestPure once or twice per day on days 14 through 27 of the menstrual cycle, or as directed by a health care professional.
  • Menopausal and post-menopausal women: Apply 1 ml of ProgestPure once or twice per day for 25 consecutive days, followed by a 5-day break, or as directed by a health care professional.

Note: Consult your functional doctor or naturopath for dosage instructions based on your specific hormone levels.

*Results are individual and depend on your health status.

For a full description:




"Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986" was originally intended to protect drinking water sources from chemicals known to cause cancer, birth defects or other reproductive harm, and to inform citizens about exposures to such chemicals. Each year the Governor posts a list of chemicals “known to the state to cause cancer or reproductive toxicity .”

Progesterone is on the list.

Progesterone is a hormone that actually prevents cancer, it also helps with your thyroid, sleep, cycle and moods. It It is necessary for a healthy pregnancy and for bone health. Progesterone also helps reduce the typical symptoms of menopause (mood changes, hot flashes, insomnia, weight gain, thyroid disfunction, loss of libido, etc...)

There are four major flaws in the study that caused progesterone to be added to the Prop 65 warning list:  

1- The vast majority of the studies implicating progesterone were done on SYNTHETIC progesterone (progestins and other progesterone-like compounds called progestagens). These studies were NOT based on BIO-IDENTICAL progesterone (as used in our ProgestPure).  

Progestins and progestagens are similar in molecular structure to progesterone, but when they bind to progesterone receptors, their effects are amplified and more likely to cause abnormal responses– just like the ones in birth control pills.

2- The majority of the studies were done in combination with synthetic estrogens. Again,  ProgestPure does not use ANY synthetic hormones.

3-  The few studies done on bio-identical progesterone were done with excessive and unreal doses (from 10 times to 10000 times the standard recommended dose).

4- No studies were done using transdermal creams. Only oral, injected and suppository forms were used. This is important to note because hormones absorbed through the skin are metabolized differently than hormones that are administered via other means. 

Click HERE to view the study that wrongly implicated bio-identical progesterone.

We were very surprised to hear that our product would bear such a warning, despite it being one of the purest bio-identical progesterone oils available.

We created this product despite the law requiring this warning. We did it because we know how many women will experience relief of their painful symptoms. And, because we know that estrogen dominance is one of the leading causes of breast, uterine, ovarian and thyroid cancers.

Please note that our team personally use ProgestPure. 

If you have any further questions about this product please email us at



Customer Reviews

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Filter Reviews:
Linda C.
United States United States


I like how easily it absorbs into the skin.

Hormone Balance Nutritionals


United States United States

Feeling Great So Far!

Depo shot had my cycle all over the place, but I've been much calmer and sleeping better since I was off and got on this. Period pain has gone down tremendously to nearly non-existent! My mother is having less hot flashes and I'll soon be getting an order for my sister. This is a God send

Hormone Balance Nutritionals

We are so pleased to know your sleep is better, there are less hot flashes and your period pain has gone down to nearly non existent! Thank you for your review. Great news!

United States United States


This is the first progesterone product I have used and although I don't yet have menopausal symptoms, I do feel the effect of this product on my mood. It is elevated and sadness has fallen away. Thank you so much!

Hormone Balance Nutritionals

Thank you for sharing your review of progestpure Julie

A Hormone Balance Nutritionals Customer
Dianne T.
United States United States

really helped my sleep issues due to menopause

I have been experiencing major sleep disruptions due to hot flashes from menopause/hormone imbalances. Using Progestpure before bed has helped a lot. I have far less wakeups due to heat. I am going to put this one on auto-ship. It is a game changer. Thanks, Magdalena!

Hormone Balance Nutritionals

We love game changers that give us the WIN! Thank you Dianne for your feedback.

Lois K.
United States United States

Convenience of usage

I added Progestpure to my liver and digestive support arsenal to handle excess estrogen. The product came securely packed in the shipment. Nice size bottle - easy to carry for travel, glass bottle - less plastic, convenient dispenser - less mess; transdermal application - less digestive upsets. I used less oil than recommended to start off and realized that I had less PMS symptoms; especially no headaches. Its just been a month, so I will keep track of my symptoms/improvements while using Progestpure.

Hormone Balance Nutritionals

Wonderful Lois! Please keep us posted at :)