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ProgestPure - 6 Bottles

137 reviews

Natural bioidentical progesterone can normalize hormone imbalances with fewer side-effects than synthetic progestins.

    ProgestPure is a highly bioavailable and natural topical progesterone serum providing 20 mg of bioidentical progesterone in each 1 ml serving. It is made from yams - it is then modified in the lab for the progesterone molecule to resemble a human progesterone molecule.

    ProgestPure contains just four ingredients: micronized USP progesterone, dimethyl isosorbide, caprylic/capric triglyceride (from coconut), and vitamin E.

    Made with non-GMO ingredients. This product is free of parabens, mineral oil, and petroleum. 

     Suggested Use:

    • Apply 1-2 times per day to smooth skin areas, such as wrists, inner arms or thighs, throat, neck, abdomen or chest, or
    as directed by a health care practitioner.
    • For optimal use, rotate the areas of application.
    • Menstruating women: Apply 1 ml of ProgestPure once or twice per day on days 14 through 27 of the menstrual cycle, or as directed by a health care professional.
    • Menopausal and post-menopausal women: Apply 1 ml of ProgestPure once or twice per day for 25 consecutive days, followed by a 5-day break, or as directed by a health care professional.

    Note: Consult your functional doctor or naturopath for dosage instructions based on your specific hormone levels.

    For a full description:




    "Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986" was originally intended to protect drinking water sources from chemicals known to cause cancer, birth defects or other reproductive harm, and to inform citizens about exposures to such chemicals. Each year the Governor posts a list of chemicals “known to the state to cause cancer or reproductive toxicity .”

    Progesterone is on the list.

    Progesterone is a hormone that actually prevents cancer, it also helps with your thyroid, sleep, cycle and moods. It It is necessary for a healthy pregnancy and for bone health. Progesterone also helps reduce the typical symptoms of menopause (mood changes, hot flashes, insomnia, weight gain, thyroid disfunction, loss of libido, etc...)

    There are four major flaws in the study that caused progesterone to be added to the Prop 65 warning list:  

    1- The vast majority of the studies implicating progesterone were done on SYNTHETIC progesterone (progestins and other progesterone-like compounds called progestagens). These studies were NOT based on BIO-IDENTICAL progesterone (as used in our ProgestPure).  

    Progestins and progestagens are similar in molecular structure to progesterone, but when they bind to progesterone receptors, their effects are amplified and more likely to cause abnormal responses– just like the ones in birth control pills.

    2- The majority of the studies were done in combination with synthetic estrogens. Again,  ProgestPure does not use ANY synthetic hormones.

    3-  The few studies done on bio-identical progesterone were done with excessive and unreal doses (from 10 times to 10000 times the standard recommended dose).

    4- No studies were done using transdermal creams. Only oral, injected and suppository forms were used. This is important to note because hormones absorbed through the skin are metabolized differently than hormones that are administered via other means. 

    Click HERE to view the study that wrongly implicated bio-identical progesterone.

    Magdalena was very surprised to hear that her product would bear such a warning, despite it being one of the purest bio-identical progesterone oils available.

    Magdalena created this product despite the law requiring this warning. She did it because she knows how many women will experience relief of their painful symptoms. And, because she knows that estrogen dominance is one of the leading causes of breast, uterine, ovarian and thyroid cancers.

    Please note that Magdalena personally uses ProgestPure. 

    If you have any further questions about this product please email us at



    Customer Reviews
    4.9 Based on 137 Reviews
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    Filter Reviews:
    Jennifer E.
    United States United States

    It helps me to sleep at night!

    Deborah H.
    United States United States
    Peace of mind

    Since using ProgestPure, I have noted my mind is calmer and I am sleeping better!! Also noted my chin hair growth slowed down. WOW!

    Hormone Balance Nutritionals

    So glad to hear of these positive changes

    Allison V.
    United States United States
    Clean option for progesterone replacement

    For those looking for a "clean" option for progesterone replacement this is an excellent choice. This also come in very small packaging so if you have concerns with storage then this is also an excellent choice for that reason as well. The only downside to this product is the dosing. If you require larger amounts of progesterone then you may find that the amount of skin surface area required for your dosage is daunting, LOL! One dropper full of 20mg is just about the amount equivalent to rubbing it in on my thighs or forearms. It does dry quickly and this is an issue with dream bases as well. However other companies offer different percentages of progesterone per the same amount of base material (such as oil or cream). Something to keep in mind if you require a higher dosage and a high maintenance self care routine :) Applying and allowing the oil to dry takes about 10 minutes for me each evening. Overall I'm very impressed and thankful to have this product!

    Hormone Balance Nutritionals

    Thank you for all of your feedback Allison. So glad you are liking our ProgestPure

    Amber R.
    United States United States
    Quality product

    Great product, has made a significant difference for me in easing my symptoms of low progesterone, fast shipping too!

    Hormone Balance Nutritionals

    Very nice Amber

    Blanche B.
    United States United States
    Progest pure serum

    I used it on my wrists one day that I was very moody for no reason & I could feel it working within just a few minutes. It just eases the tension.

    Hormone Balance Nutritionals